Substance intoxication primarily works through external chemical hijacking of reward circuits , often weakening executive control and increasing dependency risk. Meditative states arise through intentional modulation of attention and autonomic systems , strengthening executive networks and emotional regulation over time. One bypasses regulation through chemistry. The other trains regulation through neuroplasticity. Important Scientific Nuance Not all substances are equivalent (e.g., psychedelics under clinical supervision show different neural patterns than alcohol abuse). Meditation is not universally benign; intensive practices can occasionally precipitate anxiety or depersonalization in vulnerable individuals. Context, dosage, and psychological predisposition matter significantly. Substance Intoxication vs. Meditation-Induced Altered States (Neuroscience-Based Comparison) Domain Substance-Induced Intoxication (Alcohol / Psychoactive Drugs) Meditation / Contemplat...
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