Substance intoxication primarily works through external chemical hijacking of reward circuits , often weakening executive control and increasing dependency risk. Meditative states arise through intentional modulation of attention and autonomic systems , strengthening executive networks and emotional regulation over time. One bypasses regulation through chemistry. The other trains regulation through neuroplasticity. Important Scientific Nuance Not all substances are equivalent (e.g., psychedelics under clinical supervision show different neural patterns than alcohol abuse). Meditation is not universally benign; intensive practices can occasionally precipitate anxiety or depersonalization in vulnerable individuals. Context, dosage, and psychological predisposition matter significantly. Substance Intoxication vs. Meditation-Induced Altered States (Neuroscience-Based Comparison) Domain Substance-Induced Intoxication (Alcohol / Psychoactive Drugs) Meditation / Contemplat...
AI in Healthcare Prompt Thinking for Clinicians Practical Lesson for Doctors Dear Colleagues, AI in healthcare is not a magic oracle. It is a probabilistic reasoning assistant . The quality of its output depends directly on the clarity, structure, and clinical precision of your prompt . Better Prompt → Better Context → Better Clinical Output Why Prompt Clarity Is Critical AI systems: Do not “see” your patient Do not infer missing data reliably Do not replace clinical judgment If inputs are vague, outputs will be vague. If inputs are structured, outputs become clinically actionable. Garbage in = Hallucination out. Structured in = Safe assistive reasoning out. The C.L.E.A.R. Prompt Framework for Doctors Use this mental checklist before prompting AI: C – Context (Clinical Background) Always include: Age, Gender Setting (OPD/IPD/ICU/ER) Key symptoms (duration, severity) Vital signs Relevant labs/imaging Comorbidities Current medications 🔎 AI cannot guess missing clinical context. L ...