Dr.Srinivasa Raju

  The HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) is a simple, widely used mathematical index to estimate insulin resistance from routine blood tests. It is not a direct lab test but a calculation based on fasting blood glucose and fasting insulin levels.  It helps detect early insulin resistance, which is a key driver of prediabetes, type 2 diabetes, fatty liver (MASLD), metabolic syndrome, PCOS, and related conditions—especially relevant in India where these issues are rising rapidly. How the HOMA-IR Test Is Performed You need to be fasting for at least 8–12 hours (usually overnight). A blood sample is drawn to measure: Fasting plasma glucose (in mg/dL or mmol/L) Fasting insulin (in μU/mL or μIU/mL) No special preparation beyond fasting; it's often done alongside routine sugar tests. Calculation Formulas There are two common versions depending on units: Most widely used (SI units, common internationally and in many Indian labs) : HOMA-IR = (Fasting insu...