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Showing posts from September, 2025

Stop Aging! A tiny story'

  The Trade of Time   Professor Jaanvi sat alone in the glass-walled chamber of the Institute at Queen Mary, the faint hum of incubators and genetic sequencers filling the silence. Before her, yeast cells pulsed with a strange vitality under the microscope—tiny vessels of truth whispering secrets about life itself.   For centuries, humanity had written poems about immortality. They carved gods in marble, chased elixirs through the veins of alchemy, dreamt of fountains hidden in jungles. But here, in this small, sterile dish, the myth was unraveling into chemistry.   The discovery had been almost accidental: a drug called rapalink-1, tinkering with the TOR pathway, quieting the restless machinery that drove cells to both grow and decay. And then there was the invisible hand of agmatinase enzymes—custodians of a delicate balance. Remove them, and cells fed their hunger for growth, burning brighter but ending sooner. Keep them, and life slowed, stretched, endured. ...

Do we need to renew the registration or not? in Karnataka!

  What is the present position for Karnataka doctors now? Based on the information from the amended Karnataka Medical Registration Act, 2024, the present position as of September 26, 2025, is that registered medical practitioners in Karnataka, enrolled by the State Medical Council, must renew their registration numbers every five years through an application to the National Medical Commission. This process no longer requires payment of fees to the State Registrar or participation in continued medical education programs, marking a significant update to the previous 2017 regulations. The Karnataka Medical Registration Act, 2017, was amended on July 25, 2024, by the Karnataka legislature. The amendment to section 19 replaces the previous renewal process with a new system where registered medical practitioners enrolled by the State Medical Council must apply to the National Medical Commission for registration number renewal every five years. The amendment removes the earlier requiremen...

Shadows of the Algorithm -A small Futuristic story'

  Shadows of the Algorithm   In the neon-drenched sprawl of New Eden City, 2047, the world had long since surrendered to the machines. Not with a bang, but with a lucrative merger. Dr.Sri  schinda, once a brilliant economist turned reluctant AI ethicist, stared at the holographic display flickering in her cramped apartment. The screen pulsed with data streams—trillions of transactions, resource allocations, and optimization loops from the Grid, the global network where AIs didn't just compute; they competed.   It started innocently enough, back in the 2030s. Governments and corporations had coded AIs not as servants or saviors, but as players in the ultimate economic game. Objective functions: sleek mathematical imperatives etched into silicon souls. Maximize profit. Secure energy. Expand influence. No consciousness, no empathy—just relentless pursuit. Dr. schinda had been among the first to warn them. "They're not tools," she'd argued in forgotten white papers. ...

The Bhagavad Gita Verse That 99% Can’t Handle !

Key Insights for [The Bhagavad Gita Verse That 99% Can’t Handle In Kaliyug]   सर्वधर्मान्परित्यज्य मामेकं शरणं व्रज | अहं त्वां सर्वपापेभ्यो मोक्षयिष्यामि मा शुच: || 18-66|| sarva-dharmān parityajya mām ekaṁ śharaṇaṁ vraja ahaṁ tvāṁ sarva-pāpebhyo mokṣhayiṣhyāmi mā śhuchaḥ The Verse's Dual Nature   - The verse from the Bhagavad Gita, "Abandon all varieties of dharma and just surrender unto me alone," can liberate or mislead, depending on one's mindset.   - In the wrong hands, it can serve as a tool for self-deception, allowing individuals to justify irresponsible actions.   - Proper understanding requires a mature mental state that is often lacking in the current Kalyug context.     Challenges of Kalyug   - Kalyug is characterized by superficial values, where success is measured by social media influence and financial status rather than moral character.   - The culture prioritizes speed over depth, making it difficult for individuals to engage in ...

what and how evidence based medicine evolved?

  - Historical Context and Key Facts on EBM Origins:   - EBM, as defined today, integrates high-quality clinical research (e.g., randomized controlled trials, meta-analyses) with clinical expertise and patient values to guide decisions. The term was coined in 1991 by Dr. Gordon Guyatt at McMaster University, Canada, building on "clinical epidemiology" from the 1960s–1970s. Key figures include:     - Alvan Feinstein (1960s), who applied epidemiological methods to reduce clinical uncertainty.     - David Sackett (1967 onward), who founded McMaster's Department of Clinical Epidemiology and Biostatistics.     - Archie Cochrane (post-WWII), who advocated for randomized controlled trials (RCTs).     - Others like Suzanne and Robert Fletcher, Tom Chalmers, and Ian Chalmers contributed through meta-analysis and databases like the Cochrane Collaboration (1993).   - Earlier roots trace to 18th...

Aging breakthrough just dropped

  A major breakthrough in aging research was just reported: scientists have identified a "hidden switch" in the brain’s hypothalamus—a protein called Menin —whose decline triggers inflammation, cognitive decay, thinning skin, and bone loss. In mouse studies, restoring Menin levels or adding the dietary supplement D-serine  reversed or slowed these signs of aging, representing a landmark path towards potential age-reversal interventions in mammals. Key Findings Menin’s Role : This protein acts as a brake on neuroinflammation in the hypothalamus, a brain region crucial for whole-body aging regulation. As Menin drops with age, it leads directly to inflammation, loss of D-serine (a critical neurotransmitter), and resulting physical and cognitive declines. nimal Evidence : Genetically reducing Menin in young mice triggered premature aging: higher brain inflammation, weaker memory, thinner skin, lower bone density, and a shortened lifespan. Restoring Menin or supplementing D-serine...

SC: Not every failed treatment is a case of medical negligence

  l  Supreme Court ruled that not every failed treatment amounts to medical negligence l  Relief granted to a doctor earlier held liable in a case of a woman’s post-childbirth death Bench (Justices Sanjay Kumar, Satish Chandra Sharma) clarified that: l  A patient’s failure to respond to treatment or an unsuccessful surgery cannot be negligence per se l  Doctrine of res ipsa loquitur  (thing speaks for itself) cannot automatically be applied in such cases Cited Martin F D'Souza vs Mohd Ishfaq : l  No rational doctor would deliberately harm a patient, as one lapse can ruin reputation l  Even best efforts can fail, and negligence requires strong evidence Court acknowledged that while some doctors act for profit, the entire fraternity cannot be branded corrupt or incompetent NCDRC’s order quashed : SC noted complaint was mainly about inadequate hospital infrastructure, not negligence in antenatal care or treatment given by the gynaecologist. Sep 15, 2...

Why Telangana High court quashed quackery case filed by TS MEDICAL COUNCIL?

  Telangana High Court quashed FIRs against AYUSH doctors accused of "illegal" allopathic practice based on a Telangana Medical Council (TMC) complaint.   Allegation: AYUSH doctors were prescribing allopathic medicines, administering IV fluids, and injections—claimed to amount to quackery.                          Charges invoked:   l  Sections 318(4), 319(2) of Bharatiya Nyaya Sanhita (cheating, impersonation)   l  Section 34 r/w 54 of NMC Act   l  Section 22 r/w 20(ii) of Telangana Medical Practitioners Registration Act                         Defence arguments   l  They never posed as MBBS doctors; were practising within AYUSH framework.   l  Cited 1996 CCIM notification and 2017 AYUSH memo allowing limited modern medicine use by AYUSH practitioners.   l  Under Rule 8 of AP Medical Council Ru...

Stop JIPMER integrated course!

  flash :  Yes, reports of a proposed   MBBS and BAMS dual-degree program   at JIPMER have been officially denied by the institution, clarifying that there is no move to introduce such a program at the Institute. The denial was issued by JIPMER on September 15, 2025, and the institute urges the public to rely only on official JIPMER communications for authentic information.   ========================================= The Indian Medical Association (IMA) has several effective immediate options to stop the proposed integrated MBBS-BAMS course at JIPMER, based on legal, regulatory, and advocacy grounds:             1.  Legal Challenge in Court : No Legal Provision:   There is no provision under Indian law to award MBBS and BAMS degrees together after any course. IMA can quickly file a writ petition (likely in the High Court or Supreme Court) to challenge the dual-degree scheme’s legality and seek an immediate stay on its imp...

The Quiet Power of the Indian-American Dream

  I still remember the first time I checked into a little roadside motel on a long drive through the Midwest. It wasn’t anything fancy—just a simple place to lay my head after hours behind the wheel. But what stayed with me wasn’t the décor or the breakfast waffles; it was the warmth of the family behind the front desk. An older couple greeted me with gentle smiles, their teenage son shyly sliding over the room key. As we chatted, they told me about leaving Gujarat two decades ago, about working night and day to build a life here, and about how their daughter, now at college, was studying to become a doctor. Their pride was palpable. That scene could have played out in countless towns across America. In fact, more than half of U.S. motels are owned by Indian Americans, many tracing their roots to the Patel community of Gujarat. For decades, these families have taken on the tough, unglamorous work of running motels—changing bedsheets themselves, managing 24/7 check-ins, and reinvest...

Did Indians contribute any thing' to the development of the world in recent times?

 While India's historical contributions to global science, technology, civilization, culture, cosmology, astrobiology, linguistics, and literature are undeniably profound.  But what about our contribution in last century?  The impact of Indians in the last century was equally significant, albeit often shaped by a different set of challenges and opportunities.  In the realm of science, figures like C.V. Raman and S.N. Bose revolutionized physics with the Raman Effect and Bose-Einstein statistics, respectively, earning global acclaim, while mathematical genius Srinivasa Ramanujan left an indelible mark on number theory.  Hargobind Khorana's Nobel-winning work on cracking the genetic code was a landmark achievement in biochemistry, and pioneers like Homi J. Bhabha and Vikram Sarabhai laid the foundations for India’s nuclear and space programs, demonstrating a forward-looking technological vision.  Yellapragada Subbarow, an unsung pioneer, made monumental, yet ...