Breakthroughs in metabolic medicine To start, 2025 brought new breakthroughs in metabolic medicine , which is good timing: almost 4 billion adults are expected to have overweight or obesity by 2050. 1. Fatty liver disease Semaglutide became the second drug approved to treat severe fatty liver disease (MASH) — probably the most interesting medical condition hardly anyone’s heard of. It’s common (5% of people), progresses in a stepwise (but interruptible) manner, and has potentially serious complications (liver cirrhosis, liver failure, cancer). The first approval for this condition was only in 2024 , but the pipeline is now red hot , with four drugs in phase 3, eight in phase 2, and three combination therapies being trailed, too. 2.LDL cholesterol It was a good year for prevention of cardiovascular disease — and particularly for PCSK9 inhibition as a mode-of-action, which stimulates the uptake of LDL cholesterol fro...
Essential nutrients run the entire operating system of your body. The importance of minerals cannot be understated Every heartbeat, every muscle contraction, every memory, every immune response, minerals are behind it. Here’s what you’re looking at: Calcium: not just for bones It also drives nerve signaling, muscle contraction, blood clotting, and hormone release. Magnesium: the quiet multitasker It’s required for hundreds of biochemical reactions, from energy production to DNA repair to blood pressure control. Zinc: your immune system’s “on switch” It helps build proteins, repair tissues, support growth, and regulate immune cells. Iron: oxygen delivery Without iron, hemoglobin can’t carry oxygen, and your cells can’t produce energy. Potassium: the electrical system It stabilizes heart rhythm, nerve function, and fluid balance. Sodium: the regulator Essential for fluid balance, blood pressure, and nerve impulses. Copper: the builder Needed for red blood cells, col...